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February 21, 2017

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Treatment of CD20-directed Chimeric Antigen Receptor...

February 23, 2017. Safety, Activity, and Immune Correlates of Anti–PD-1... (http://www.nejm.org/doi/full/10.1056/NEJMoa1200690) The Immune Tolerance Network is a collaborative network for clinical research focused on the development of therapeutic approaches for asthma and allergy, autoimmune...

February 25, 2017
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The Immune Tolerance Network is a collaborative network for clinical research focused on the development of therapeutic approaches for asthma and allergy, autoimmune...

February 27, 2017. History of Diabetes: American Diabetes Association® (http://www.diabetes.org/research-and-practice/stude nt-resources/history-of-diabetes.html) Type 1 diabetes is a chronic illness characterized by the body’s inability to produce insulin due to the autoimmune destruction of the beta cells in the...

March 02, 2017
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Clinical protocol design. Patients with tumors that had a diameter <5 cm or who had ⩽ 3 lesions provided samples of peripheral blood mononuclear cells from which...

February 26, 2017
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Predictive correlates of response to the anti-PD-L1...

March 01, 2017

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Type 1 diabetes mellitus - Diapedia, The Living Textbook...

February 22, 2017
Sirolimus (INN/USAN), also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare... i5
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February 24, 2017
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February 28, 2017
Cytokine Storm in a Phase 1 Trial of the Anti-CD28... i7
Original Article. Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer. Suzanne L. Topalian, M.D., F. Stephen Hodi, M.D., Julie R. Brahmer, M.D...

March 19, 2017

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Peregrine Pharmaceuticals (PPHM) Stock Message Board...

March 22, 2017. Anti-Slan (M-DC8) antibodies, human - Miltenyi Biotec (http://www.miltenyibiotec.com/en/products-and-servi ces/macs-flow-cytometry/reagents/antibodies-and-dye s/anti-slan-m-dc8-antibodies-human.aspx) Description/Summary: Cancer immunotherapy is the use of the immune system to fight cancer. ERY974 is a bispecific antibody designed to elicit T cell activation and T...

March 16, 2017
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Pipeline. Rigorous and groundbreaking science has always been at the core of what we do at Genentech. Our R&D activities are focused on applying excellent science to...

March 17, 2017. Omalizumab - Wikipedia (https://en.wikipedia.org/wiki/Omalizumab) Type 1 diabetes is a disease that involves many genes. The risk of a child developing type 1 diabetes is about 5% if the father has it, about 8% if a sibling has it...

March 25, 2017
Safety and immunogenicity of the tau vaccine AADvac1 in... i2
Description/Summary: Cancer immunotherapy is the use of the immune system to fight cancer. ERY974 is a bispecific antibody designed to elicit T cell activation and T...

March 20, 2017
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Type 1 diabetes is a disease that involves many genes. The risk of a child developing type 1 diabetes is about 5% if the father has it, about 8% if a sibling has it...

March 21, 2017

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Roche - Pipeline

March 24, 2017
The Anti-Slan (M-DC8) antibody (clone DD-1) recognizes Slan (6-Sulfo LacNAc), which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This... i5
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March 18, 2017

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Aetna Clinical Policy Bulletin 0264: Multiple sclerosis...

March 23, 2017
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April 20, 2017

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Multiple Sclerosis - Aetna

April 21, 2017
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April 14, 2017
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April 16, 2017
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April 12, 2017

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Diabetes Drugs and Medication in Development

April 17, 2017
BUPLEURUM: Uses, Side Effects, Interactions and Warnings... i5
Six healthy young male volunteers at a contract research organization were enrolled in the first phase 1 clinical trial of TGN1412, a novel superagonist anti-CD28...

April 18, 2017
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April 19, 2017
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April 15, 2017

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BETA-GLUCANS: Uses, Side Effects, Interactions and...

April 13, 2017
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May 12, 2017

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Product pipeline | GSK

May 09, 2017
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Rosuvastatin to Prevent Vascular Events in Men and Women...

May 13, 2017
Diabetes drug treatments currently in development. New drug treatments for Type 1 and Type 2 diabetes; New drug treatments for Type 2 diabetes; New drug treatments... i2
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May 08, 2017
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Immunosuppression after solid organ transplantation is complex. Over the past 50 years, the medical community has witnessed great advances in the care of...

May 10, 2017

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Immunosuppression: Overview, History, Drugs

May 11, 2017
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May 16, 2017
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Rosuvastatin to Prevent Vascular Events in Men and Women...

May 07, 2017

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Immunosuppression: Overview, History, Drugs

May 14, 2017
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June 09, 2017

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Journal of Diabetes and its Complications

June 11, 2017. Journal of Diabetes and its Complications (http://www.jdcjournal.com/) I would add, "that although type 1 diabetes is the most frequent diabetes form in children/ puberty/ young adults, about half of the cases are diagnosed at adult age...

June 03, 2017
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June 06, 2017
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June 04, 2017
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June 07, 2017

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes...

June 05, 2017
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June 08, 2017
Histiocytosis Clinical Presentation: History... i6
World Gastroenterology Organisation Global Guidelines. Celiac disease. July 2016. Review Team. Julio C. Bai (Chair, Argentina), Carolina Ciacci (Co-chair, Italy...

July 05, 2017

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Type 1 Diabetes Mellitus Treatment & Management: Approach...

July 02, 2017. Diagnosis and Management of Celiac Disease | American... (http://gi.org/guideline/diagnosis-and-management-of -celiac-disease/) Original Article. Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus. Kevan C. Herold, M.D., William Hagopian, M.D., Ph.D., Julie A. Auger, B.A., Ena...

July 04, 2017

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Type 1 Diabetes Mellitus Treatment & Management: Approach...

July 29, 2017

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Molecular Therapy Family of Journals: Cell Press

July 30, 2017. Insulin Needs after CD3-Antibody Therapy in New-Onset Type... (http://www.nejm.org/doi/full/10.1056/NEJMoa043980) Six healthy young male volunteers at a contract research organization were enrolled in the first phase 1 clinical trial of TGN1412, a novel superagonist anti-CD28...

July 28, 2017

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Genetics, pathogenesis and clinical interventions in type...

August 24, 2017

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Low-Dose Otelixizumab Anti-CD3... - Home | Diabetes Care

August 25, 2017. Low-Dose Otelixizumab Anti-CD3... - Home | Diabetes Care (http://care.diabetesjournals.org/content/37/10/2746.full) Type 1 Diabetes; Clinical Trial... II clinical study in which two doses of anti-CD3... onset type 1 diabetes. After 2 years, the anti-CD3-treated group...

August 22, 2017

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New Publication: Partial Exhaustion of CD8 T Cells in...

September 14, 2017

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PAR-14-064: Research Using Subjects From Selected Type I...

September 18, 2017. RFA-DK-14-016: Type 1 Diabetes TrialNet Clinical Centers (U01) (https://grants.nih.gov/grants/guide/rfa-files/RFA-D K-14-016.html) Current Funding Opportunities. Open grant, contract, and cooperative agreement listings with closing dates and contacts. Research Programs & Contacts

September 20, 2017

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The Compelling Case for Anti-CD3 in Type 1 Diabetes

September 16, 2017. Diabetes Research: Improving Lives on the Path to a Cure 2015 (https://www.niddk.nih.gov/about-niddk/budget-legisl ative-information/diabetes-research-improving-lives -on-the-path-to-a-cure/Pages/default.aspx) Type 1 diabetes (T1D) is a chronic autoimmune disease that leads to progressive destruction of pancreatic beta cells. Compared to healthy controls, a characteristic...

October 17, 2017

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Can We Prevent Type 1 Diabetes? | SpringerLink

October 14, 2017. Targeting Memory T Cells in Type 1 Diabetes | SpringerLink (https://link.springer.com/article/10.1007/s11892-01 5-0659-5) News and updates on potential cures for type-1 diabetes, that are in human (or clinical) trials. "In vitae veritate"

October 13, 2017

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Can We Prevent Type 1 Diabetes? | SpringerLink

November 07, 2017

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EBV infection and anti-CD3 treatment for Type 1 diabetes...

November 13, 2017. Type 1 diabetes drug strikingly effective in clinical trial (https://www.sciencedaily.com/releases/2013/08/13080 7155152.htm) Two humanized, anti-CD3 mAbs with reduced FcR binding, teplizumab and otelixizumab, have been evaluated in over 1500 subjects, ages 7-45, with new and recently...

December 12, 2017

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Anti-CD3 Monoclonal Antibody Slows New-Onset Type 1 Diabetes

December 11, 2017. Anti-CD3 clinical trials in type 1 diabetes... - DeepDyve (https://www.deepdyve.com/lp/elsevier/anti-cd3-clini cal-trials-in-type-1-diabetes-mellitus-DUQJzwA2KF) This is a randomized placebo controlled study to test whether a single 14 course of treatment with the anti-CD3 monoclonal antibody, hOKT3gamma1(Ala-Ala),Teplizumab...

December 06, 2017

Comments about this video:

Remodeling T cell compartments during anti-CD3...

December 07, 2017. AntiCD3 Mab (Teplizumab) For Prevention of Diabetes In... (https://www.centerwatch.com/clinical-trials/listing s/139945/anticd3-mab-teplizumab-for-prevention-of-d iabetes-in-relatives-at-risk-for-type-1-diabetes-me llitus-2/) Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes S. Alice Long, Jerill Thorpe, Kevan C. Herold... AbATE clinical trial.


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